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Aberrant mRNA transcripts and nonsense-mediated decay

Nobody's perfect, and even the cell turns out a certain fraction of erroneous mRNA transcripts. One of the key quality control mechanisms put in place to recognize and eliminate these transcripts before they can be translated into faulty proteins is nonsense-mediated decay. Proteins involved in...

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Bibliographic Details
Main Author: Trinkle-Mulcahy, Laura
Format: Artigo
Language:Inglês
Published: Biology Reports 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948277/
https://ncbi.nlm.nih.gov/pubmed/20948598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-93
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