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Two mechanisms that account for major histocompatibility complex restriction of T cells

In recent studies, two distinct mechanisms have been proposed to account for major histocompatibility complex (MHC) restriction of T-cell activity: (a) evolution-driven interactions between T-cell receptor (TCR) variable regions and MHC, and (b) a requirement for CD4 or CD8 binding to MHC to initiat...

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Detalhes bibliográficos
Autor principal: Kranz, David M
Formato: Artigo
Idioma:Inglês
Publicado em: Biology Reports Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948262/
https://ncbi.nlm.nih.gov/pubmed/20948629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-55
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