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Two mechanisms that account for major histocompatibility complex restriction of T cells
In recent studies, two distinct mechanisms have been proposed to account for major histocompatibility complex (MHC) restriction of T-cell activity: (a) evolution-driven interactions between T-cell receptor (TCR) variable regions and MHC, and (b) a requirement for CD4 or CD8 binding to MHC to initiat...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biology Reports Ltd
2009
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948262/ https://ncbi.nlm.nih.gov/pubmed/20948629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-55 |
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