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Promotion and Regulation of Homologous Recombination by DNA Helicases
In eukaryotes, homologous recombination (HR) provides an important means to eliminate DNA double-stranded breaks and other chromosomal lesions. Accordingly, failure in HR leads to genomic instability and a predisposition to various cancer types. While HR is clearly beneficial for genome maintenance,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948243/ https://ncbi.nlm.nih.gov/pubmed/20156560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.02.009 |
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