A cyclic-RGD-BioShuttle functionalized with TMZ by DAR(inv) “Click Chemistry” targeted to α(v)β(3) integrin for therapy

Clinical experiences often document, that a successful tumor control requires high doses of drug applications. It is widely believed that unavoidable adverse reactions could be minimized by using gene-therapeutic strategies protecting the tumor-surrounding healthy tissue as well as the bone-marrow....

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Autors principals: Braun, Klaus, Wiessler, Manfred, Pipkorn, Rüdiger, Ehemann, Volker, Bäuerle, Tobias, Fleischhacker, Heinz, Müller, Gabriele, Lorenz, Peter, Waldeck, Waldemar
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948216/
https://ncbi.nlm.nih.gov/pubmed/20922134
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