Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry

Recurrent glioblastoma multiforme (GBM), insensitive against most therapeutic interventions, has low response and survival rates. Temozolomide (TMZ) was approved for second-line therapy of recurrent anaplastic astrocytoma. However, TMZ therapy in GBM patients reveals properties such as reduced toler...

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Detalhes bibliográficos
Main Authors: Braun, Klaus, Wiessler, Manfred, Ehemann, Volker, Pipkorn, Ruediger, Spring, Herbert, Debus, Juergen, Didinger, Bernd, Koch, Mario, Muller, Gabriele, Waldeck, Waldemar
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761188/
https://ncbi.nlm.nih.gov/pubmed/19920915
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