Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry

Recurrent glioblastoma multiforme (GBM), insensitive against most therapeutic interventions, has low response and survival rates. Temozolomide (TMZ) was approved for second-line therapy of recurrent anaplastic astrocytoma. However, TMZ therapy in GBM patients reveals properties such as reduced toler...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Braun, Klaus, Wiessler, Manfred, Ehemann, Volker, Pipkorn, Ruediger, Spring, Herbert, Debus, Juergen, Didinger, Bernd, Koch, Mario, Muller, Gabriele, Waldeck, Waldemar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2009
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761188/
https://ncbi.nlm.nih.gov/pubmed/19920915
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