Role of reduced intensity conditioning in T-cell and B-cell immune reconstitution after HLA-identical bone marrow transplantation in ADA-SCID

The treatment of choice for severe combined immunodeficiency is bone marrow transplantation from an HLA-identical donor sibling without conditioning. However, this may result in low donor stem cell chimerism, leading to reduced long-term immune reconstitution. We compared engraftment, metabolic, and...

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Main Authors: Cancrini, Caterina, Ferrua, Francesca, Scarselli, Alessia, Brigida, Immacolata, Romiti, Maria Luisa, Barera, Graziano, Finocchi, Andrea, Roncarolo, Maria Grazia, Caniglia, Maurizio, Aiuti, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2010
Assuntos:
Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948105/
https://ncbi.nlm.nih.gov/pubmed/20460637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.025098
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