Φορτώνει......

Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients

Mutations in the adenosine deaminase (ADA) gene are responsible for a form of severe combined immunodeficiency (SCID) caused by the lymphotoxic accumulation of ADA substrates, adenosine and 2′-deoxy-adenosine. The molecular mechanisms underlying T-cell dysfunction in humans remain to be elucidated....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Cassani, Barbara, Mirolo, Massimiliano, Cattaneo, Federica, Benninghoff, Ulrike, Hershfield, Michael, Carlucci, Filippo, Tabucchi, Antonella, Bordignon, Claudio, Roncarolo, Maria Grazia, Aiuti, Alessandro
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2008
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288726/
https://ncbi.nlm.nih.gov/pubmed/18218852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-092429
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!