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MICA polymorphism identified by whole genome array associated with NKG2D-mediated cytotoxicity in T-cell large granular lymphocyte leukemia

BACKGROUND: Large granular lymphocyte leukemia is a semi-autonomous clonal proliferation of cytotoxic T cells accompanied by immune cytopenias and various autoimmune conditions. Due to the rarity of this disease and its association with autoimmune diseases, a theoretical germline or somatic mutation...

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Detalhes bibliográficos
Main Authors: Viny, Aaron D., Clemente, Michael J., Jasek, Monika, Askar, Medhat, Ishwaran, Hemant, Nowacki, Amy, Zhang, Aiwen, Maciejewski, Jaroslaw P.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948097/
https://ncbi.nlm.nih.gov/pubmed/20460636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.021865
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