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Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation
Regulation of chromatin structure via histone modification has received intense recent attention. Here, we demonstrate that the chromatin modifying enzyme histone deacetylase 2 (Hdac2) functions with a small homeodomain factor, Hopx, to mediate deacetylation of Gata4, which is expressed by cardiac p...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947937/ https://ncbi.nlm.nih.gov/pubmed/20833366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.08.012 |
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