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Effective shutdown in the expression of celiac disease-related wheat gliadin T-cell epitopes by RNA interference

Celiac disease (CD) is an enteropathy triggered by the ingestion of gluten proteins from wheat and similar proteins from barley and rye. The inflammatory reaction is controlled by T cells that recognize gluten peptides in the context of human leukocyte antigen (HLA) DQ2 or HLA-DQ8 molecules. The onl...

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Auteurs principaux: Gil-Humanes, Javier, Pistón, Fernando, Tollefsen, Stig, Sollid, Ludvig M., Barro, Francisco
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947919/
https://ncbi.nlm.nih.gov/pubmed/20829492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007773107
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