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Protein-induced photophysical changes to the amyloid indicator dye thioflavin T

The small molecule thioflavin T (ThT) is a defining probe for the identification and mechanistic study of amyloid fiber formation. As such, ThT is fundamental to investigations of serious diseases such as Alzheimer’s disease, Parkinson disease, and type II diabetes. For each disease, a different pro...

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Detalhes bibliográficos
Main Authors: Wolfe, Leslie S., Calabrese, Matthew F., Nath, Abhinav, Blaho, Dorottya V., Miranker, Andrew D., Xiong, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947910/
https://ncbi.nlm.nih.gov/pubmed/20826442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002867107
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