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Hyperaccurate and error-prone ribosomes exploit distinct mechanisms during tRNA selection

Escherichia coli strains displaying hyper-accurate (restrictive) and ribosomal ambiguity (ram) phenotypes have long been associated with alterations in rpsL and rpsD/rpsE, respectively. Crystallographic evidence shows the ribosomal proteins S12 and S4/S5 (corresponding to these genes) to be located...

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Main Authors: Zaher, Hani S., Green, Rachel
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947859/
https://ncbi.nlm.nih.gov/pubmed/20603079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.009
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