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Endoglin Plays Distinct Roles in Vascular Smooth Muscle Cell Recruitment and Regulation of Arteriovenous Identity During Angiogenesis

Blood vessel formation is a multi-step process. Endoglin is a TGFβ coreceptor required for angiogenesis. Endoglin null embryos exhibit a loss of arteriovenous identity and defective vascular smooth muscle cell (vSMC) recruitment. Haploinsufficiency of endoglin results in Hereditary Hemorrhagic Telan...

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Main Authors: Mancini, Maria L., Terzic, Aleksandra, Conley, Barbara A., Oxburgh, Leif H., Nicola, Teodora, Vary, Calvin P.H.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947792/
https://ncbi.nlm.nih.gov/pubmed/19705428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22066
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