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Endoglin Plays Distinct Roles in Vascular Smooth Muscle Cell Recruitment and Regulation of Arteriovenous Identity During Angiogenesis
Blood vessel formation is a multi-step process. Endoglin is a TGFβ coreceptor required for angiogenesis. Endoglin null embryos exhibit a loss of arteriovenous identity and defective vascular smooth muscle cell (vSMC) recruitment. Haploinsufficiency of endoglin results in Hereditary Hemorrhagic Telan...
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Auteurs principaux: | , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947792/ https://ncbi.nlm.nih.gov/pubmed/19705428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22066 |
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