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A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst

The inner cell mass (ICM) of the implanting mammalian blastocyst comprises two lineages: the pluripotent epiblast (EPI) and primitive endoderm (PrE). We have identified platelet-derived growth factor receptor alpha (PDGFRα) as an early marker of the PrE lineage and its derivatives in both mouse embr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Artus, Jérôme, Panthier, Jean-Jacques, Hadjantonakis, Anna-Katerina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947752/
https://ncbi.nlm.nih.gov/pubmed/20826533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.050864
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