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Lipopolysaccharide potentiates effector T cell accumulation into non-lymphoid tissues through TRIF ,

LPS is a natural adjuvant that potentiates antigen (Ag)-specific T cell survival and Th1 differentiation by stimulating MyD88 and TRIF signaling pathways. Here, we reveal the TRIF pathway is critical for amplifying murine effector T cell accumulation into non-lymphoid tissues following immunization...

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Bibliographic Details
Main Authors: McAleer, Jeremy P., Rossi, Robert J., Vella, Anthony T.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947744/
https://ncbi.nlm.nih.gov/pubmed/19380779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803616
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