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The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro

The P2X7 receptor (P2X7R) has been implicated in the process of multinucleation and cell fusion. We have previously demonstrated that blockade of P2X7Rs on osteoclast precursors using a blocking antibody inhibited multinucleated osteoclast formation in vitro, but that P2X7R KO mice maintain the abil...

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Detalhes bibliográficos
Main Authors: Agrawal, Ankita, Buckley, Katherine A., Bowers, Keith, Furber, Mark, Gallagher, James A., Gartland, Alison
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947658/
https://ncbi.nlm.nih.gov/pubmed/21103214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-010-9181-z
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