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Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts

Multiple myeloma is a malignant expansion of plasma cells and aggressively affects bone health. We show that P2X7 receptor altered myeloma growth, which affects primary bone cells in vitro. Expression on six human myeloma cell lines confirmed the heterogeneity associated with P2X7 receptor. Pharmaco...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Agrawal, Ankita, S. Kruse, Lars, J. Vangsted, Annette, Gartland, Alison, R. Jørgensen, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690412/
https://ncbi.nlm.nih.gov/pubmed/33105696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112341
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