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Reduced sample sizes for atrophy outcomes in Alzheimer's disease trials: baseline adjustment

Cerebral atrophy rate is increasingly used as an outcome measure for Alzheimer's disease (AD) trials. We used the Alzheimer's disease Neuroimaging initiative (ADNI) dataset to assess if adjusting for baseline characteristics can reduce sample sizes. Controls (n = 199), patients with mild c...

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Bibliografski detalji
Glavni autori: Schott, J.M., Bartlett, J.W., Barnes, J., Leung, K.K., Ourselin, S., Fox, N.C.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947486/
https://ncbi.nlm.nih.gov/pubmed/20620665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.04.011
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