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Inhibition and repression of homocitrate synthase by lysine in Penicillium chrysogenum.

Homocitrate synthase in the first enzyme of the lysine biosynthetic pathway. It is feedback regulated by L-lysine. Lysine decreases the biosynthesis of penicillin (determined by the incorporation of [14C]valine into penicillin) by inhibiting and repressing homocitrate synthase, thereby depriving the...

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Библиографические подробности
Опубликовано в: :J Bacteriol
Главные авторы: Luengo, J M, Revilla, G, López, M J, Villanueva, J R, Martín, J F
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1980
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6777369/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.144.3.869-876.1980
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