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Inhibition and repression of homocitrate synthase by lysine in Penicillium chrysogenum.

Homocitrate synthase in the first enzyme of the lysine biosynthetic pathway. It is feedback regulated by L-lysine. Lysine decreases the biosynthesis of penicillin (determined by the incorporation of [14C]valine into penicillin) by inhibiting and repressing homocitrate synthase, thereby depriving the...

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Detalhes bibliográficos
Main Authors: Luengo, J M, Revilla, G, López, M J, Villanueva, J R, Martín, J F
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC294747/
https://ncbi.nlm.nih.gov/pubmed/6777369
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