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Investigational EGFR-targeted therapies in HNSCC

IMPORTANCE OF THE FIELD: The epidermal growth factor receptor (EGFR) is an established therapeutic target in head and neck squamous cell carcinoma (HNSCC). The EGFR-targeting monoclonal antibody cetuximab (™Erbitux) was FDA-approved for use in HNSCC in 2006. The molecular basis for the efficacy of a...

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Detalhes bibliográficos
Main Authors: Cassell, Andre, Grandis, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947445/
https://ncbi.nlm.nih.gov/pubmed/20415598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543781003769844
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