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Synthesis of Peptide-Oligonucleotide Conjugates Using a Heterobifunctional Crosslinker

Peptide-oligonucleotide conjugates (POCs) are molecular chimeras composed of a nucleic acid moiety covalently attached to a polypeptide moiety. POCs have been used in numerous applications from therapeutics to nanotechnology, and most recently as combinatorial agents in the assembly of bivalent prot...

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Autors principals: Williams, Berea A.R., Chaput, John C.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947322/
https://ncbi.nlm.nih.gov/pubmed/20827717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142700.nc0441s42
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