Constant p53 Pathway Inactivation in a Large Series of Soft Tissue Sarcomas with Complex Genetics

Alterations of the p53 pathway are among the most frequent aberrations observed in human cancers. We have performed an exhaustive analysis of TP53, p14, p15, and p16 status in a large series of 143 soft tissue sarcomas, rare tumors accounting for around 1% of all adult cancers, with complex genetics...

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Detalhes bibliográficos
Main Authors: Pérot, Gaëlle, Chibon, Frédéric, Montero, Audrey, Lagarde, Pauline, de Thé, Hugues, Terrier, Philippe, Guillou, Louis, Ranchère, Dominique, Coindre, Jean-Michel, Aurias, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947301/
https://ncbi.nlm.nih.gov/pubmed/20884963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100104
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