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HLA-E–restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes
A key feature of the immune system is its ability to discriminate self from nonself. Breakdown in any of the mechanisms that maintain unresponsiveness to self (a state known as self-tolerance) contributes to the development of autoimmune conditions. Recent studies in mice show that CD8(+) T cells sp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947239/ https://ncbi.nlm.nih.gov/pubmed/20877010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43522 |
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