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The specificity of T cell regulation that enables self-nonself discrimination in the periphery

It was recently shown that perceiving the avidity of T cell activation can be translated into peripheral T cell regulation to control autoimmune disease. This regulation is achieved by CD8(+) T cells that recognize a common surrogate target structure, Qa-1/Hsp60sp, preferentially expressed by activa...

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Detalhes bibliográficos
Main Authors: Wu, Yilun, Zheng, Zongyu, Jiang, Yihua, Chess, Leonard, Jiang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613037/
https://ncbi.nlm.nih.gov/pubmed/19118203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811843106
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