Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer

Platinum-based chemotherapies such as cisplatin are used as first-line treatment for many cancers. Although there is often a high initial responsiveness, the majority of patients eventually relapse with platinum-resistant disease. For example, a subset of testicular cancer patients still die even th...

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Detalhes bibliográficos
Main Authors: Koster, Roelof, di Pietro, Alessandra, Timmer-Bosscha, Hetty, Gibcus, Johan H., van den Berg, Anke, Suurmeijer, Albert J., Bischoff, Rainer, Gietema, Jourik A., de Jong, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947220/
https://ncbi.nlm.nih.gov/pubmed/20811155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41939
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