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Casein Kinase 2 Regulates the NR2 Subunit Composition of Synaptic NMDA Receptors

NMDA receptors (NMDARs) play a central role in development, synaptic plasticity and neurological disease. NMDAR subunit composition defines their biophysical properties and downstream signaling. Casein kinase 2 (CK2) phosphorylates the NR2B subunit within its PDZ-binding domain; however, the consequ...

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Bibliografiske detaljer
Main Authors: Sanz-Clemente, Antonio, Matta, Jose A., Isaac, John T.R., Roche, Katherine W.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947143/
https://ncbi.nlm.nih.gov/pubmed/20869595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.08.011
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