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Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2
The chloride ion channel cystic fibrosis transmembrane conductance regulator (CFTR) displays a typical adenosine trisphosphate (ATP)-binding cassette (ABC) protein architecture comprising two transmembrane domains, two intracellular nucleotide-binding domains (NBDs), and a unique intracellular regul...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947058/ https://ncbi.nlm.nih.gov/pubmed/20876359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010434 |
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