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Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2

The chloride ion channel cystic fibrosis transmembrane conductance regulator (CFTR) displays a typical adenosine trisphosphate (ATP)-binding cassette (ABC) protein architecture comprising two transmembrane domains, two intracellular nucleotide-binding domains (NBDs), and a unique intracellular regul...

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Detalhes bibliográficos
Main Authors: Szollosi, Andras, Vergani, Paola, Csanády, László
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947058/
https://ncbi.nlm.nih.gov/pubmed/20876359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010434
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