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Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax
An abrupt increase of intracellular Ca(2+) is observed in cells under hypoxic or oxidatively stressed conditions. The dysregulated increase of cytosolic Ca(2+) triggers apoptotic cell death through mitochondrial swelling and activation of Ca(2+)-dependent enzymes. Transglutaminase 2 (TG2) is a Ca(2+...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Korean Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947021/ https://ncbi.nlm.nih.gov/pubmed/20676023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.9.063 |
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