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Anxiolytic-like Effects of the Neurokinin 1 Receptor Antagonist GR-205171 in the Elevated Plus-Maze and Contextual Fear-Potentiated Startle Model of Anxiety in Gerbils

Gerbils show a NK1 receptor pharmacological profile which is similar to that seen in humans and thus have become a commonly used species to test efficacy of NK1 receptor antagonists. The aim of the present study was to determine whether systemic administration of the NK1 receptor antagonist GR-20517...

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Bibliographic Details
Main Authors: Heldt, Scott A., Davis, Michael, Ratti, Emiliangelo, Corsi, Mauro, Trist, David, Ressler, Kerry J.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946835/
https://ncbi.nlm.nih.gov/pubmed/19675456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32832ec594
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