Clustering-based identification of clonally-related immunoglobulin gene sequence sets

BACKGROUND: Clonal expansion of B lymphocytes coupled with somatic mutation and antigen selection allow the mammalian humoral immune system to generate highly specific immunoglobulins (IG) or antibodies against invading bacteria, viruses and toxins. The availability of high-throughput DNA sequencing...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Zhiliang, Collins, Andrew M, Wang, Yan, Gaëta, Bruno A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Proceedings
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946782/
https://ncbi.nlm.nih.gov/pubmed/20875155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-S1-S4
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