Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS

One of the hallmarks of B lymphoid malignancies is a B cell clone characterized by a unique footprint of clonal immunoglobulin (IG) gene rearrangements that serves as a diagnostic marker for clonality assessment. The EuroClonality/BIOMED-2 assay is currently the gold standard for analyzing IG heavy...

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Publicado no:Leukemia
Main Authors: Scheijen, Blanca, Meijers, Ruud W. J., Rijntjes, Jos, van der Klift, Michèle Y., Möbs, Markus, Steinhilber, Julia, Reigl, Tomas, van den Brand, Michiel, Kotrová, Michaela, Ritter, Julia-Marie, Catherwood, Mark A., Stamatopoulos, Kostas, Brüggemann, Monika, Davi, Frédéric, Darzentas, Nikos, Pott, Christiane, Fend, Falko, Hummel, Michael, Langerak, Anton W., Groenen, Patricia J. T. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756030/
https://ncbi.nlm.nih.gov/pubmed/31197258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0508-7
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