Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response

Mismatch repair proteins modulate the cytotoxicity of several chemotherapeutic agents. We have recently proposed a “death conformation” of the MutS homologous proteins that is distinguishable from their “repair conformation.” This conformation can be induced by a small molecule, reserpine, leading t...

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Detalhes bibliográficos
Main Authors: Vasilyeva, Aksana, Clodfelter, Jill E., Gorczynski, Michael J., Gerardi, Anthony R., King, S. Bruce, Salsbury, Freddie, Scarpinato, Karin D.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946608/
https://ncbi.nlm.nih.gov/pubmed/20936178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/162018
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