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PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1
Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines. Rac1 GTPase enhances colon cancer cell migration and invasion. Here we report a positive correlation between PTHrP expression and Rac1 activity in LoVo (human colon cancer) cells. The positive effec...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946490/ https://ncbi.nlm.nih.gov/pubmed/20637541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.06.009 |
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