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PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1

Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines. Rac1 GTPase enhances colon cancer cell migration and invasion. Here we report a positive correlation between PTHrP expression and Rac1 activity in LoVo (human colon cancer) cells. The positive effec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mula, Ramanjaneya V., Bhatia, Vandanajay, Falzon, Miriam
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946490/
https://ncbi.nlm.nih.gov/pubmed/20637541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.06.009
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