Timed inhibition of p38MAPK directs accelerated differentiation of human embryonic stem cells into cardiomyocytes

BACKGROUND AIMS: Heart failure therapy with human embryonic stem cell (hESC)-derived cardiomyocytes (hCM) has been limited by the low rate of spontaneous hCM differentiation. As others have shown that p38 mitogen-activated protein kinase (p38MAPK) directs neurogenesis from mouse embryonic stem cells...

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Hlavní autoři: GAUR, MEENAKSHI, RITNER, CARISSA, SIEVERS, RICH, PEDERSEN, ANISSA, PRASAD, MEGHA, BERNSTEIN, HAROLD S., YEGHIAZARIANS, YEREM
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946443/
https://ncbi.nlm.nih.gov/pubmed/20586669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2010.491821
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