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Timed inhibition of p38MAPK directs accelerated differentiation of human embryonic stem cells into cardiomyocytes
BACKGROUND AIMS: Heart failure therapy with human embryonic stem cell (hESC)-derived cardiomyocytes (hCM) has been limited by the low rate of spontaneous hCM differentiation. As others have shown that p38 mitogen-activated protein kinase (p38MAPK) directs neurogenesis from mouse embryonic stem cells...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946443/ https://ncbi.nlm.nih.gov/pubmed/20586669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2010.491821 |
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