The second extracellular loop dictates Occludin-mediated HCV entry

Recent findings have implicated tight junction (TJ) protein Occludin (OCLN) as an essential factor for Hepatitis C Virus (HCV) to enter human hepatocytes. To gain insights into OCLN-mediated HCV entry, we created a panel of OCLN deletion mutants and found that without impairing OCLN’s cell surface l...

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Detalhes bibliográficos
Main Authors: Liu, Shufeng, Kuo, Wayne, Yang, Wei, Liu, Weiqun, Gibson, Gregory A., Dorko, Kenneth, Watkins, Simon C., Strom, Stephen C., Wang, Tianyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946412/
https://ncbi.nlm.nih.gov/pubmed/20822789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.08.009
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