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A Common Variant in the Telomerase RNA Component Is Associated with Short Telomere Length

BACKGROUND: Telomeres shorten as cells divide. This shortening is compensated by the enzyme telomerase. We evaluated the effect of common variants in the telomerase RNA component (TERC) gene on telomere length (TL) in the population-based Health Aging and Body Composition (Health ABC) Study and in t...

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Detalhes bibliográficos
Main Authors: Njajou, Omer T., Blackburn, Elizabeth H., Pawlikowska, Ludmila, Mangino, Massimo, Damcott, Coleen M., Kwok, Pui-Yan, Spector, Timothy D., Newman, Anne B., Harris, Tamara B., Cummings, Steven R., Cawthon, Richard M., Shuldiner, Alan R., Valdes, Ana M., Hsueh, Wen-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946401/
https://ncbi.nlm.nih.gov/pubmed/20885959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013048
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