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Telomere length is paternally inherited and is associated with parental lifespan

Telomere length (TL) is emerging as a biomarker for aging and survival. To evaluate factors influencing this trait, we measured TL in a large homogeneous population, estimated the heritability (h(2)), and tested for parental effects on TL variation. Our sample included 356 men and 551 women, aged 18...

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Detalhes bibliográficos
Main Authors: Njajou, Omer T., Cawthon, Richard M., Damcott, Coleen M., Wu, Shih-Hsuan, Ott, Sandy, Garant, Michael J., Blackburn, Elizabeth H., Mitchell, Braxton D., Shuldiner, Alan R., Hsueh, Wen-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924539/
https://ncbi.nlm.nih.gov/pubmed/17623782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702703104
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