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Identification of mutant phenotypes associated with loss of individual microRNAs in sensitized genetic backgrounds in Caenorhabditis elegans

MicroRNAs (miRNAs) are small, non-coding RNAs that regulate the translation and/or the stability of their mRNA targets. Previous work showed that for most miRNA genes of C. elegans, single gene knockouts did not result in detectable mutant phenotypes [1]. This may be due, in part, to functional redu...

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Detalhes bibliográficos
Main Authors: Brenner, John L., Jasiewicz, Kristen L., Fahley, Alisha F., Kemp, Benedict J., Abbott, Allison L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946380/
https://ncbi.nlm.nih.gov/pubmed/20579881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.05.062
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