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α(2)-Adrenergic receptor blockade potentiates the effect of duloxetine, a serotonin and norepinephrine reuptake inhibitor, on sneeze-induced urethral continence reflex in rats

PURPOSE: Serotonin and norepinephrine reuptake inhibitors (SNRI) such as duloxetine have demonstrated clinical efficacy in the treatment of stress urinary incontinence (SUI). However, the therapeutic dose of duloxetine is often associated with unwanted side effects. In the present study, we examined...

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Hlavní autoři: Kitta, Takeya, Miyazato, Minoru, Chancellor, Michael B., de Groat, William C., Nonomura, Katsuya, Yoshimura, Naoki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946347/
https://ncbi.nlm.nih.gov/pubmed/20639053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2010.03.106
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