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α(2)-Adrenergic receptor blockade potentiates the effect of duloxetine, a serotonin and norepinephrine reuptake inhibitor, on sneeze-induced urethral continence reflex in rats
PURPOSE: Serotonin and norepinephrine reuptake inhibitors (SNRI) such as duloxetine have demonstrated clinical efficacy in the treatment of stress urinary incontinence (SUI). However, the therapeutic dose of duloxetine is often associated with unwanted side effects. In the present study, we examined...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946347/ https://ncbi.nlm.nih.gov/pubmed/20639053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2010.03.106 |
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