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Solution Structure of a Nonpolar, Non-Hydrogen-Bonded Base Pair Surrogate in DNA

We describe the structure in aqueous solution of a DNA duplex containing a base pair that is structurally analogous to A–T but which lacks hydrogen bonds. Base analogues F (a nonpolar isostere of thymine) and Z (a nonpolar isostere of adenine) are paired opposite one another in a 12 base pair duplex...

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Main Authors: Guckian, Kevin M., Krugh, Thomas R., Kool, Eric T.
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946154/
https://ncbi.nlm.nih.gov/pubmed/20882115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja994164v
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