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The Receptor-Dependent Actions of 1,25-Dihydroxyvitamin D Are Required for Normal Growth Plate Maturation in NPt2a Knockout Mice

Rickets is a growth plate abnormality observed in growing animals and humans. Rachitic expansion of the hypertrophic chondrocyte layer of the growth plate, in the setting of hypophosphatemia, is due to impaired apoptosis of these cells. Rickets is observed in humans and mice with X-linked hypophosph...

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Detalhes bibliográficos
Main Authors: Miedlich, Susanne U., Zhu, Eric D., Sabbagh, Yves, Demay, Marie B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946147/
https://ncbi.nlm.nih.gov/pubmed/20685875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0354
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