Mechanism of cAMP regulation of renin gene transcription by proximal promoter.

Renin is produced mainly by the kidney, and cAMP is a main positive regulator of its synthesis. This study was undertaken to analyze the molecular mechanism of cAMP-mediated regulation of Ren-1C gene transcription by the proximal promoter. We first showed that the promoter region from -365 to +16 of...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Tamura, K, Umemura, S, Yamaguchi, S, Iwamoto, T, Kobayashi, S, Fukamizu, A, Murakami, K, Ishii, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7962542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117547
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