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A combination of upstream and proximal elements is required for efficient expression of the mouse renin promoter in cultured cells.
Renin, a key enzyme controlling blood pressure, is produced mainly in the kidney. To identify the transcriptional regulatory elements of the mouse Ren-1c gene, the promoter regions were fused to the CAT reporter gene and transfected into embryonic kidney-derived 293 cells and four extrarenal cell li...
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| 發表在: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
1992
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| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1641328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.14.3617 |
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