Tpl2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1β production

Tumor progression locus 2 (Tpl2, also known as Map3k8 and Cot) is a serine-threonine kinase critical in innate immunity, linking toll-like receptors (TLRs) to tumor necrosis factor (TNF) production through its activation of extracellular signal-regulated kinase (ERK). Tpl2(−/−) macrophages have abro...

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Detaylı Bibliyografya
Asıl Yazarlar: Mielke, Lisa A., Elkins, Karen L., Wei, Lai, Starr, Robyn, Tsichlis, Philip N., O'Shea, John J., Watford, Wendy T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946069/
https://ncbi.nlm.nih.gov/pubmed/19933865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901336
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