Up-Regulation of α4β7 Integrin on Peripheral T Cell Subsets Correlates with the Development of Acute Intestinal Graft-versus-Host Disease following Allogeneic Stem Cell Transplantation

Acute graft-versus-host disease (aGVHD) is a major complication after hematopoietic stem cell transplantation (HSCT). The pathophysiology of aGVHD involves priming of naïve donor T cells in host secondary lymphoid tissue, followed by migration of effector T cells to target organs. Mediators of lymph...

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Main Authors: Chen, Yi-Bin, Kim, Haesook T., McDonough, Sean, Odze, Robert D., Yao, Xiaopan, Lazo-Kallanian, Suzan, Spitzer, Thomas R., Soiffer, Robert, Antin, Joseph H., Ritz, Jerome
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945817/
https://ncbi.nlm.nih.gov/pubmed/19660719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2009.05.003
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