Characterization of the Time Course of Carbamazepine Deinduction by an Enzyme Turnover Model

BACKGROUND AND OBJECTIVE: Carbamazepine is a potent inducer of drug metabolizing enzymes, which results in a number of clinically significant drug-drug interactions. Deinduction occurs when chronic carbamazepine therapy is discontinued. The goal of this study was to develop a population pharmacokine...

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Main Authors: Punyawudho, B., Cloyd, J.C., Leppik, I.E., Ramsay, R.E., Marino, S.E., Pennell, P.B., White, J.R., Birnbaum, A.K.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945813/
https://ncbi.nlm.nih.gov/pubmed/19566114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/00003088-200948050-00003
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